Pi-Hole is a network-wide ad blocker.
It is very easy to install and maintain.
Configure Pi-Hole behind NginX
Query which list is blocking a particular domain
Setting up Pi-hole as a recursive DNS server
Setup Pi-Hole running in a container on QNAP Container Station
Setup Pi-Hole running in Docker
Setup Pi-Hole running in Docker and Portainer
Setup Pi-Hole running in Ubuntu